What are the Brain Abnormalities Associated with Schizophrenia?
Increasing evidence suggests that certain areas of the brain including the limbic system and basal ganglia may play an important role in the pathophysiology of schizophrenia. Because these areas are connected functionally, dysfunction in one area could lead to dysfunction in other areas. In addition, brain imaging studies have revealed abnormalities in brain structure and function that are associated with schizophrenia.
Limbic SystemWhat is Limbic System? The limbic system is the emotional center of the brain. It consists of several interconnected structures within the cerebral hemispheres and diencephalon (e.g., the thalamus, hypothalamus, and hippocampus), and plays a key role in emotion, learning, and memory.. |
Basal GangliaWhat is Basal Ganglia? As you may recall, the basal ganglia are a group of nuclei that are located in the frontal lobes and that are involved in the selection and initiation of willed movement and in coordinating muscle activity initiated by the cerebral cortex. |
Brain Imaging in SchizophreniaWhat are the Brain Imaging Studies in Schizophrenia? Three key imaging techniques that have revealed brain abnormalities in people with schizophrenia are magnetic resonance imaging, computed tomography, and positron emission tomography. |
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