Pharmacologic Therapies in Schizophrenia

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What are the factors that affect the choice of Pharmacologic Therapies in Schizophrenia?

Since the discovery of the first antipsychotic medication in the 1950s, numerous typical and atypical agents have been developed. While no medication can cure schizophrenia, antipsychotics can effectively treat many key symptoms. Compared with those who receive antipsychotics, about two to four times as many patients who receive placebo will relapse. When selecting an antipsychotic for a patient, physicians may take into consideration not only the known properties of the agent (e.g., its efficacy in addressing specific symptoms and any known adverse effects), but also such factors as:

  • past response to treatment
  • severity of the illness
  • need for polypharmacy (multiple medications)
  • preferred form of administration (e.g., injectable vs. oral)
  • cost

Typical Antipsychotics & Schizophrenia

What is the roles of Typical Antipsychotics in schizophrenia? These are first generation antipsychotics.

Atypical Antipsychotics & Schizophrenia

What is the role of Atypical Antipsychotics in schizophrenia? These are second generation antipsychotics.
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Schizophrenia Pharmacologic Therapies